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Cardiovascular System: Within days of initial exposure to hypoxia, autonomic nervous system adjustments result in increased heart rate and cardiac output, optimizing oxygen delivery to tissues throughout the body, thus protecting the heart from excessive workload due to increased metabolic demands

Laboratory and method

Example: One patient from Arizona came to us because, despite being maximized on treatment for Rheumatoid arthritis with DMARDs and a biologic, her disease control was very poor

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Maas AI, Menon DK, Manley GT, Abrams M, kerlund C, Andelic N, et al

Subcutaneous injection avoids this risk entirely