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In 3-AR knockout mice, however, no effect was observed with AOD9604 confirming the dependency of its chronic lipolytic action on 3-AR expression, while also suggesting an additional acute mechanism that may operate through a separate pathway

Second, they reduce oxidative stress

Eur J Drug Metab Pharmacokinet 1991, 3648 Frolich J, Seccombe DW, Hahn P, et al

Metrika 55 , 125138 (2002)