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Some of it is not safe

Key Nutrients Depleted by Corticosteroids Corticosteroids are associated with depletion of multiple nutrients essential for tissue repair, immune defense, and metabolic stability, including: Calcium, vitamin D, magnesium, potassium, zinc, selenium, vitamin C, and protein (1) Mechanisms of Steroid-Induced Nutrient Depletion Calcium & vitamin D: Reduced intestinal absorption and increased urinary loss osteopenia and fracture risk Zinc, selenium & vitamin C: Impaired immune function, delayed wound healing, increased infection risk Protein: Accelerated protein breakdown muscle wasting and connective tissue weakness Magnesium & potassium: Electrolyte imbalance fatigue, weakness, and cardiac rhythm disturbances Why Steroid-Induced Nutrient Depletion Impairs Healing By chronically elevating cortisol signaling, corticosteroids shift the body into a catabolic, stress-dominant state

Cancer Res 66 , 32143221 (2006)

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The result is that the mainly oil soluble, emollient fatty alcohol is converted to an emulsifier molecule that keeps oil and water mixed in creams

Purification, properties, and mechanism of action [PMID: 6035915] Laboratory literature summary: Tripeptide (glutathione) synthetase