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Left unaddressed, severe cases may progress to Barretts esophagus, a precancerous condition requiring ongoing medical surveillance

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Perl A, Hanczko R, Lai ZW, Oaks Z, Kelly R, Borsuk R et al (2015) Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycin