Springer, Singapore
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It is correct to state that many of the hormones involved in metabolism influence each others action by both indirect and direct mechanisms to promote metabolic homeostasis, as discussed in this review
One of the studies was done on the elderly which showed a reduction in physical and mental fatigue
Thus, integration of both hormones into a single molecule may not only maximize the metabolic efficacy of the individual signals, but allow also specific delivery of estrogen into GLP1 receptor-expressing cells, avoiding potential undesired effects of estrogen on reproductive tissues, as shown also in our studies
By regularly tracking these metrics, you and your healthcare provider can determine how effective the therapy is and tweak your plan if needed