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The fractional labeling of Rib5P revealed a different pattern between iPSCs and differentiating neurons, with neurons showing higher overall labeling as well as an increase in the M + 3 isotopomer at 360 min, suggesting alterations in the PPP (Fig
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It features a lactam bridge cyclization between Aspartic Acid and Lysine residues, which significantly enhances its stability against enzymatic degradation compared to linear peptides
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