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5FU-resistant organoids were generated through chronic exposure to 5FU

DECLARATIONS Authors contributions Developed the model, ran simulations and analyses, interpreted the findings, and contributed to the writing and editing of the manuscript: Cruikshank A, Reed MC, Nijhout HF Availability of data and materials Computer models and codes used in this paper can be obtained from the authors by request

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It is prepared by licensed 503A compounding pharmacies for individual use based on a valid prescription

If you experience persistent vomiting or diarrhoea, contact your healthcare provider, as monitoring of renal function may be necessary

Food changes: Portions, snacks, drinks, and alcohol can shift calories