Furthermore, a dual luciferase reporter system assay demonstrated that the luciferase activity of GGCT-3 untranslated region (UTR) (wild-type) decreased after transfection with miR-29b-3p mimics, while the luciferase activity of GGCT-3 mUTR (mut) did not show significant changes in MHCC97H and LNCaP cells (Fig
It helps fuel metabolic processes, supports mitochondrial health, and contributes to overall vitality
More importantly, PKM2 can translocate into the nucleus, where it regulates the transcription of metabolic genes such as HIF-1, LDHA, and GLUT1, thereby enhancing glycolysis, suppressing OXPHOS, and establishing a metabolic firewall against therapeutic stress [97]
Among them, GPX1-4 and 6 are selenocysteine-containing proteins
Watermelon, apples, bananas, pears and peaches are also safe fruit choices
Remove the needle from the vial carefully