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PMID: 17597598 Belosic Halle O, et al

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Activation of these receptors in the brain (particularly brainstem and hypothalamic regions) suppresses appetite, reduces food intake through both homeostatic and hedonic pathways, slows gastric emptying to prolong fullness, and inhibits postprandial glucagon release to aid glucose control

Clinical Weight Loss Results In a 12-week randomized clinical trial involving 300 obese adults, subjects receiving 1 mg daily of AOD-9604 lost an average of 2.6 kg compared to 0.8 kg in the placebo group

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