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Semaglutide therapy is generally recommended for individuals with a body mass index (BMI) of 27 kg/m or higher and who have at least one weight-related comorbidity (such as type 2 diabetes or high blood pressure)

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These categories are organized by physiological domain and translational barrier rather than by peptide family or receptor class, reflecting the cross-cutting nature of underexploration

doi: 10.1002/oby.23371