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As you lose weight, your baseline metabolic rate also decreases because a smaller body requires fewer calories to maintain itself
This partial reversal may be driven by factors such as compliance challenges, waning drug efficacy, or measurement limitations
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The secondary endpoint was time from randomization to first occurrence of an expanded composite cardiovascular outcome, defined as MACE, revascularization (coronary and peripheral), unstable angina requiring hospitalization or hospitalization for heart failure
It blocks cleavage by dipeptidyl peptidase-4
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