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Considering muscle mass maintenance and the putatively beneficial effects of ketosis, KDs and STS should be compared with chronic CR or protein restriction in clinical studies
The relationship between obesity and bone metabolism is paradoxical, as increased mechanical loading is traditionally associated with higher bone mineral density, yet adiposity-driven chronic inflammation and metabolic dysfunction impair bone quality
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Routine concerns about QT prolongation or cardiac conduction effects with chlorphenamine are not well established
But for the right patient, the improvement in comfort, confidence, clothing fit, and body proportions can be life-changing
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