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Whole-transcriptome brain expression and exon-usage profiling in major depression and suicide: evidence for altered glial, endothelial and ATPase activity

It is therefore possible to assume that in clinical trials in which neurodegenerative diseases were alleviated, mitophagy and autophagy were also enhanced

Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway

This pathway influences how cells respond to stress and growth signals, potentially extending lifespan by enhancing stress resistance and cellular survival mechanisms

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Its also interesting that lower levels of this chemical have been found in women with a history of childhood trauma and childhood trauma is a well known risk factor for the development of depression