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Some users report better subjective results with subcutaneous AOD 9604 than the oral formulation used in trials, but controlled data supporting those anecdotal reports does not exist at a level that would change the fundamental comparison
Injectable GHK-Cu is a systemic subcutaneous dose given at the four standard body sites
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Importantly, in the same paper the anti-obesity efficacy experiment in diet-induced obese mice was carried out by systemic administration of the inhibitor the researchers did not report an oral-gavage efficacy arm
Novo reported that, in a late-stage study, a next-generation obesity drug called CagriSema led patients to lose 20% of their weight at 68 weeks when looking at all participants less than the companys own projection of about 25% weight loss
