Chonluten and other organ-specific bioregulators represent a strategy of supporting tissue health alongside immune modulation, addressing both the cause and the consequences of autoimmune inflammation simultaneously
Immunohistochemistry showed positive reaction to anti-FSH-b antibody (1:200 dilution, Leica, Wetzlar, Germany) and a-subunit (Roche, Basel, Switzerland), but negative reaction to all other pituitary hormones including LH-b (1:400 dilution, Leica) (Figure 3B,C,D)
Horopito (Kolorex): Horopito ( Pseudowintera colorata ) has antifungal and anti-biofilm effectstwo clinical trials found it more effective than the drug itraconazole for vaginal Candida infections 34 35
Propionyl-L-carnitine shows particular promise for peripheral vascular disease and heart failure, with some trials demonstrating improved exercise tolerance.[8][9] LCAR supplementation improves glucolipid metabolism, reducing fasting glucose, insulin resistance, triglycerides, and liver enzymes.[10] Both compounds exhibit excellent safety profiles with minimal side-effects, though recent data raises concerns about substantial TMAO production (reaching 50 M plasma levels) from both supplements, which may have adverse cardiovascular implications.[1][8][3] References Potential Therapeutic Role of Carnitine and Acetylcarnitine in Neurological Disorders
Preclinical CagriSema data suggests it may preserve energy expenditure by maintaining mitochondrial function in skeletal muscle, which could theoretically support better muscle preservation over time
Tamura M, Ito H, Matsui H, Hyodo I (2014) Acetaldehyde is an oxidative stressor for gastric epithelial cells