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thus, no dose adjustment is required.70 The effectiveness of liraglutide combined with sitagliptin or pioglitazone has been assessed in patients with NAFLD and DM

GLP-1 medications deliver synthetic hormones through injections, often causing nausea or digestive discomfort

Think of it like fresh produce

They work through several mechanisms that are relevant even when your pancreas no longer makes insulin: they slow gastric emptying (meaning food hits your bloodstream more gradually), suppress glucagon release (the hormone that raises blood sugar), and reduce appetite

In fact, PCBP depletion was associated with loss of IRP1-mediated IRE binding activity