The mechanism underlying tirzepatide's lipid effects appears multifactorial
Premium Updated Dec 12, 2025 05:28 PM IST Shrotriya, in a candid chat with ET NOW, added that Novo Nordisk is not worried about competition even after the semaglutide patent expires in India in January 2026, stating that their focus remains on quality, clinical excellence and ensuring a steady supply
13 The latest meta-analysis shows that AN adult patients have an average reduction of 0.16 kg in whole-body bone mineral content, 14 and there is no gender difference in the reduction of BMD in adolescent patients, 15 In terms of bone microstructure, abnormalities are observed in the distal radius and distal tibia of AN patients, manifested as reduced volumetric bone mineral density (vBMD), decreased cortical bone area and thickness, increased porosity, decreased trabecular bone density and increased separation degree, but the results of studies on trabecular bone number changes are inconsistent
This isnt unusual
Liraglutide (Victoza and Saxenda) doesnt work as well (produces less weight loss) and causes more side effects, but it is a GLP-1 agonist
The approved sites are the stomach area, the thigh, or the back of the upper arm