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E., Giustarini, D., Rossi, R., Dela, F., Helge, J

The following are commonly reported findings from research literature not from personal use contexts

synthesized by certain bacteria Although the intestinal flora of humans is able to synthesize vitamin B 12 , humans are not able to absorb bacteria-generated vitamin B 12 since the location of synthesis (the colon) is too distal from the location of absorption (the small intestine)

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Later findings varied substantially according to species, route, timing and experimental conditions

This is because stomach acid plays a role in separating B12 from the protein its bound to in food, allowing for proper absorption