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When hydroxocobalamin is given in high doses (such as during cyanide poisoning treatment), unique effects can be observed: patients often experience a transient reddening of the skin or mucous membranes and a reddish discoloration of the urine due to drug excretion

In ME/CFS patients, dysfunction of the TRPM3 calcium channel, which is critical for calcium permeability and NK cell function, results in diminished NK cell activity and disrupted calcium signaling [146]

Liu W, Zhao Y, Wang G, Feng S, Ge X, Ye W, et al

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( c ) GSEA analysis of RNA-seq data from Parental and Resistant AKP organoids