Semaglutide works by mimicking the natural hormone GLP-1, which enhances insulin secretion in response to meals, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways
But in recent years, it has also been approved for weight loss under brand names, including Wegovy
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The 2025 systematic review noted that despite increasing clinical use, this level of evidence does not yet exist
Monthly weight regain was also faster after weight loss drugs than after behavioral weight management programs (by 0.3 kg), independent of initial weight loss
Personas activas y deportistas por su papel en el metabolismo lipdico