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Glutathione Treatment Side Effects Is It Safe
JAMA 2016;315:2424-34
Valemetostat, a dual EZH1/EZH2 inhibitor approved for relapsed/refractory adult T-cell leukemia/lymphoma (ATL), acts by removing H3K27me3-mediated chromatin condensation to restore tumor suppressor gene expression
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Research in stem cells has suggested an upregulation of markers associated with neuronal differentiation, which could point toward possible roles in epigenetic regulation
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