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Low-level NLRP3 activation regulates hepatic lipid metabolism via IL-18, and its absence is associated with increased steatosis

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A limitation of these studies is the absence of stratification of heart failure patients based on ejection fraction, therefore additional clinical research specifically investigating the effects of GLP-1 receptor agonists in patients with heart failure with preserved ejection fraction (HFpEF) is warranted [94]

This may enhance recovery benefits but requires consistent workout timing