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SARS-CoV-2-infected patients with COVID-19 disease show alterations in the glucoseinsulin axis leading to hyperglycemia, hyperinsulinemia and insulin resistance, increased oxidative/nitrosative stress, and significantly decreased vitamin D, thiols, total-antioxidant-capacity, GSH and selenium (Soto et al., 2022)

The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American association for the study of liver diseases

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& Scarvell, J

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This binding triggers several important physiological responses: enhanced insulin secretion from pancreatic beta cells in response to elevated blood glucose, suppression of glucagon release (which normally raises blood sugar), delayed gastric emptying (slowing food passage from stomach to intestine), and increased satiety through effects on appetite centres in the brain