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IC50 was 34.19 M, 61.53 M in the senescent fibroblasts from keloid and normal skin, and 93.77 M, 104.6 M in non-senescent control fibroblasts from keloid and normal skin, respectively

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The main enzymes involved in enzymatic reactions are uncoupled endothelial nitric oxide synthase (eNOS), NADPH oxidase (NOX), xanthine oxidase (XO), arachidonic acid (ARA), peroxidase, and metabolic enzymes such the cytochrome P450 system, cyclooxygenase, and lipoxygenase

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