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This option carries a higher risk of persistent gastrointestinal effects during escalation, so you need to closely monitor your protein intake and hydration

Case reports have described depression or mood worsening after starting semaglutide, with improvement after stopping in some reports

doi: 10.1038/s41392-022-00904-4 440 WangX.ChenL.RuanH.XiongZ.WangW.QiuJ.et al

Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy men

Adults with T2D and CKD were randomised 1:1 to receive once weekly semaglutide 1.0 mg and standard of care (mean age: 66.6 years, 29.4% female