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The kidneys are one of the bodys critical filters, supporting water and fluid balance, blood pressure regulation, and waste elimination

After the incubation, hECs were washed with Ringer-HEPES buffer (118 mM NaCl, 4.8 mM KCl, 2.5 mM CaCl 2 , 1.2 mM MgSO 4 , 5.5 mM d-glucose, 20 mM HEPES, pH 7.4) supplemented with 1% FBS

Nat Rev Gastroenterol Hepatol 21 , 664666 (2024)

Patients often experience reduced hunger and early satiety, creating risk for inadequate protein and micronutrient intake if dietary quality is poor

This is partly due to reduced food intake and partly due to increased metabolic effects from the higher dose

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