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Genetic predispositions in the GIPR, FTO, and MC4R genes influence medication responsiveness

[29] The promotion of antioxidant enzyme expression, such as superoxide dismutase, glutathione peroxidase, glutathione reductase, and catalase, is mediated through melatonin receptor-triggered signal transduction pathways

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While ROS play important roles in redox signaling and defense mechanisms, their excessive accumulation can disrupt the delicate balance of redox potential within cells, leading to oxidative stress and cell damage