Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, et al
Central nervous system mediation occurs through GLP-1 receptors in the hypothalamus and brainstem, particularly the area postrema and nucleus tractus solitarius [8]
Sleep disturbances: Some people taking Semaglutide notice changes in their sleep patterns, including trouble falling asleep, waking up frequently during the night, or feeling excessively tired during the day
Common GLP-1 agonists include: Semaglutide (Ozempic, Wegovy) Liraglutide (Victoza, Saxenda) Dulaglutide (Trulicity) Tirzepatide (Zepbound) While initially used for diabetes management, studies showed that GLP-1 agonists also contribute significantly to weight loss, leading to their approval for obesity treatment as well
Severe, steady upper abdominal pain lasting for hours and radiating to the back is the hallmark symptom
Due to popularity of the medications, GLP-1s were in short supply up until recently