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NAD+ IV can cause flushing, nausea, or mild chest tightness if infused too quickly
It is also worth noting that one of the possible mutations appeared to have a much stronger association with schizophrenia in male populations as opposed to female, probably due to the neuroprotective properties of estrogen
Tapering may be helpful if using long term (6+ weeks), but isnt physiologically necessary
Whilst vitamin B12 toxicity is exceptionally rare due to its water-soluble nature, very high levelsparticularly from mega-dose supplements or frequent injectionshave been associated with certain adverse effects, most notably skin reactions
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